Tarihi da Juyin Halitta na Rashin Inganta
Gudanar da kwayoyi na kwayoyi a karni na sha bakwai lokacin da Christopher wren allura a cikin kare ta amfani da Goover Que Que Que Que Que Que Que Que Que Que Que Que Que A cikin 1930 aka gabatar da hexobarbalit da pentotal cikin aikin asibiti.
Ya kasance a cikin shekarun 1960s na Pharmacaken da ke da ƙididdigar da daidaitawa da daidaitawa da IV Infusions kuma a cikin 1980s, kwamfuta tana gabatar da tsarin Jiko. A cikin 1996 manufa ta farko sarrafa tsarin jiko ('Diprufusor') aka gabatar.
Bayyani
A Target Gudanar da JikoJiko ne da ke sarrafa irin wannan don yunƙurin cimma mai amfani da magunguna da aka ƙayyade ko nama na sha'awa. An ba da shawarar wannan ra'ayi ta Kruger masoya a shekarar 1968.
Pharpacak
Girma na rarraba.
Wannan ne bayyananne a bayyane wanda aka rarraba miyagun ƙwayoyi. Ana lissafta ta hanyar dabara: vd = kashi / camcration na magani. Darajar ta dogara ne da aka ƙididdige shi a lokacin sifili - bayan wani bolus (VC) ko a cikin jihar gaba bayan jiko (vss).
Share.
Tsaro yana wakiltar girman plasma (VP) daga abin da aka cire maganin a kowane lokaci don aiwatar da aikinta daga jiki. CEVANCHE = Cire X VP.
Kamar yadda share ya kara rabin-rai yana raguwa, kuma kamar yadda rarraba rarrabawa yana ƙaruwa don haka ne rabin rayuwa. Hakanan za'a iya amfani da shi don bayyana yadda da sauri magani yana motsawa tsakanin sassan. An rarraba miyagun ƙwayoyi a farkon dakin karatun kafin rarraba zuwa sassan jikin. Idan farkon rarraba rarraba (VC) da kuma maida hankali ne ga warkewa sakamako (CP), yana yiwuwa a lissafa nauyin Loading:
Loading kashi = CP X VC
Hakanan za'a iya amfani dashi don lissafa ƙimar Bolus don saurin maida hankali a lokacin ci gaba da jiko: bolus kashi = (cluss - cactutu) x Vc. Adadin jiko don ci gaba da kasancewa a tsaye jihar = CP X X.
Matsakaicin jingin Ja-sauyi ba su cimma matsaya na jihar plasma ba har akalla akalla biyar da kewayon rabin rayuwa. Za'a iya samun nasarar tattarawa da sauri idan an bi kashi na Bolus wanda aka bi ta hanyar jiko.
Lokaci: Nuwamba-04-2023